Biotin - avitin system ( bas ) was used to immobilize dna on the pdms channel compared to the direct immobilization methds . the hybridization reaction also has been examined between immobilized probe and target dna 针对pdms新型材料,试验了两种dna分子的固定方法,确定了生物素?亲和素介导的dna分子固定化方法,并使用此芯片和固定方法进行了芯片上的dna杂交反应。